Antioxidant gene expression in the blood-feeding fly Glossina morsitans morsitans

被引：34

作者：

Munks, RJL

Sant'Anna, MRV

Grail, W

Gibson, W

Igglesden, T

Yoshiyama, M

Lehane, SM

Lehane, MJ

机构：

[1] Univ Liverpool, Liverpool Sch Trop Med, Liverpool L3 5QA, Merseyside, England

[2] Univ Coll N Wales, Sch Biol Sci, Bangor LL57 2UW, Gwynedd, Wales

[3] Univ Bristol, Sch Biol Sci, Bristol, Avon, England

来源：

INSECT MOLECULAR BIOLOGY | 2005年 / 14卷 / 05期

基金：

英国惠康基金;

关键词：

Glossina; antioxidant; trypanosome; immunity; haem;

D O I：

10.1111/j.1365-2583.2005.00579.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We report the characterization of 11 antioxidant genes from the tsetse fly Glossina m. morsitans. Through similarity searches which detected homology we suggest that these genes consist of two superoxide dismutases (one with a putative signal peptide), three thioredoxin peroxidases (one with a putative signal peptide), three peroxiredoxins, one further signal peptide-containing peroxidase with its closest similarity to a glutathione peroxidase, one catalase and one thioredoxin reductase. We describe the changes occurring in the expression levels of these genes during fly development, in different adult tissues, in the adult midgut through the digestive cycle and following trypanosome infection. Overall, nine of the 11 genes studied showed responses to changes in physiological circumstance, with the peroxiredoxin group showing the smallest variations throughout.

引用

收藏

页码：483 / 491

页数：9

相关论文

共 34 条

[11] ISOLATION AND SEQUENCE OF COMPLEMENTARY-DNA ENCODING HUMAN EXTRACELLULAR SUPEROXIDE-DISMUTASE [J].

HJALMARSSON, K ;

MARKLUND, SL ;

ENGSTROM, A ;

EDLUND, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (18) :6340-6344

[12]

Jordan A. M., 1986, TRYPANOSOMIASIS CONT

[13] Substitution of the thioredoxin system for glutathione reductase in Drosophila melanogaster [J].

Kanzok, SM ;

Fechner, A ;

Bauer, H ;

Ulschmid, JK ;

Müller, HM ;

Botella-Munoz, J ;

Schneuwly, S ;

Schirmer, RH ;

Becker, K .

SCIENCE, 2001, 291 (5504) :643-646

[14] Profiling catalase gene expression in Drosophila melanogaster during development and aging [J].

Klichko, VI ;

Radyuk, SN ;

Orr, WC .

ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY, 2004, 56 (01) :34-50

[15] The role of reactive oxygen species on Plasmodium melanotic encapsulation in Anopheles gambiae [J].

Kumar, S ;

Christophides, GK ;

Cantera, R ;

Charles, B ;

Han, YS ;

Meister, S ;

Dimopoulos, G ;

Kafatos, FC ;

Barillas-Mury, C .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (24) :14139-14144

[16] Adult midgut expressed sequence tags from the tsetse fly Glossina morsitans morsitans and expression analysis of putative immune response genes -: art. no. R63 [J].

Lehane, MJ ;

Aksoy, S ;

Gibson, W ;

Kerhornou, A ;

Berriman, M ;

Hamilton, J ;

Soares, MB ;

Bonaldo, MF ;

Lehane, S ;

Hall, N .

GENOME BIOLOGY, 2003, 4 (10)

[17] Composition of the peritrophic matrix of the tsetse fly, Glossina morsitans morsitans [J].

Lehane, MJ ;

Allingham, PG ;

Weglicki, P .

CELL AND TISSUE RESEARCH, 1996, 283 (03) :375-384

[18] Cloning, sequencing, temporal expression and tissue-specificity of two serine proteases from the midgut of the blood-feeding fly Stomoxys calcitrans [J].

Lehane, SM ;

Assinder, SJ ;

Lehane, MJ .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1998, 254 (02) :290-296

[19] The mosquito Anopheles stephensi limits malaria parasite development with inducible synthesis of nitric oxide [J].

Luckhart, S ;

Vodovotz, Y ;

Cui, LW ;

Rosenberg, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (10) :5700-5705

[20] ARTIFICIAL FEEDING TECHNIQUE FOR GLOSSINA [J].

MOLOO, SK .

PARASITOLOGY, 1971, 63 (DEC) :507-&

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