Canalization of Tomato Fruit Metabolism

被引：54

作者：

Alseekh, Saleh ^{[1
]}

Tong, Hao ^{[1
]}

Scossa, Federico ^{[1
,2
]}

Brotman, Yariv ^{[1
,3
]}

Vigroux, Florian ^{[1
]}

Tohge, Takayuki ^{[1
]}

Ofner, Itai ^{[4
]}

Zamir, Dani ^{[4
]}

Nikoloski, Zoran ^{[1
]}

Fernie, Alisdair R. ^{[1
]}

机构：

[1] Max Planck Inst Mol Plant Physiol, D-14476 Potsdam, Germany

[2] Consiglio Ric Agr & Anal Econ Agr, I-00134 Rome, Italy

[3] Ben Gurion Univ Negev, Dept Life Sci, IL-653 Beer Sheva, Israel

[4] Hebrew Univ Jerusalem, Fac Agr, Robert H Smith Inst Plant Sci & Genet Agr, IL-76100 Rehovot, Israel

来源：

PLANT CELL | 2017年 / 29卷 / 11期

基金：

以色列科学基金会;

关键词：

QUANTITATIVE TRAIT LOCI; TRANSCRIPTION FACTOR; IDENTIFICATION; INTROGRESSION; ROBUSTNESS; YIELD; INHERITANCE; GENES; HSP90; METABOLOMICS;

D O I：

10.1105/tpc.17.00367

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

To explore the genetic robustness (canalization) of metabolism, we examined the levels of fruit metabolites in multiple harvests of a tomato introgression line (IL) population. The IL partitions the whole genome of the wild species Solanum pennellii in the background of the cultivated tomato (Solanum lycopersicum). We identified several metabolite quantitative trait loci that reduce variability for both primary and secondary metabolites, which we named canalization metabolite quantitative trait loci (cmQTL). We validated nine cmQTL using an independent population of backcross inbred lines, derived from the same parents, which allows increased resolution in mapping the QTL previously identified in the ILs. These cmQTL showed little overlap with QTL for the metabolite levels themselves. Moreover, the intervals they mapped to harbored few metabolism-associated genes, suggesting that the canalization of metabolism is largely controlled by regulatory genes.

引用

页码：2753 / 2765

页数：13

共 56 条

[1]

Robustness in bacterial chemotaxis [J].

Alon, U ;

Surette, MG ;

Barkai, N ;

Leibler, S .

NATURE, 1999, 397 (6715) :168-171

[2]

Identification and Mode of Inheritance of Quantitative Trait Loci for Secondary Metabolite Abundance in Tomato [J].

Alseekh, Saleh ;

Tohge, Takayuki ;

Wendenberg, Regina ;

Scossa, Federico ;

Omranian, Nooshin ;

Li, Jie ;

Kleessen, Sabrina ;

Giavalisco, Patrick ;

Pleban, Tzili ;

Mueller-Roeber, Bernd ;

Zamir, Dani ;

Nikoloski, Zoran ;

Fernie, Alisdair R. .

PLANT CELL, 2015, 27 (03) :485-512

[3]

[Anonymous], 2009, Mixed-Effects Models in S and S-PLUS

[4]

STABILITY ANALYSIS IN PLANT-BREEDING [J].

BECKER, HC ;

LEON, J .

PLANT BREEDING, 1988, 101 (01) :1-23

[5]

The genome of the stress-tolerant wild tomato species Solanum pennellii [J].

Bolger, Anthony ;

Scossa, Federico ;

Bolger, Marie E. ;

Lanz, Christa ;

Maumus, Florian ;

Tohge, Takayuki ;

Quesneville, Hadi ;

Alseekh, Saleh ;

Sorensen, Iben ;

Lichtenstein, Gabriel ;

Fich, Eric A. ;

Conte, Mariana ;

Keller, Heike ;

Schneeberger, Korbinian ;

Schwacke, Rainer ;

Ofner, Itai ;

Vrebalov, Julia ;

Xu, Yimin ;

Osorio, Sonia ;

Aflitos, Saulo Alves ;

Schijlen, Elio ;

Jimenez-Gomez, Jose M. ;

Ryngajllo, Malgorzata ;

Kimura, Seisuke ;

Kumar, Ravi ;

Koenig, Daniel ;

Headland, Lauren R. ;

Maloof, Julin N. ;

Sinha, Neelima ;

van Ham, Roeland C. H. J. ;

Lankhorst, Rene Klein ;

Mao, Linyong ;

Vogel, Alexander ;

Arsova, Borjana ;

Panstruga, Ralph ;

Fei, Zhangjun ;

Rose, Jocelyn K. C. ;

Zamir, Dani ;

Carrari, Fernando F ;

Giovannoni, James J. ;

Weigel, Detlef ;

Usadel, Bjoern ;

Fernie, Alisdair R. .

NATURE GENETICS, 2014, 46 (09) :1034-+

[6]

QTL mapping of fruit mineral contents provides new chances for molecular breeding of tomato nutritional traits [J].

Capel, Carmen ;

Yuste-Lisbona, Fernando J. ;

Lopez-Casado, Gloria ;

Angosto, Trinidad ;

Heredia, Antonio ;

Cuartero, Jesus ;

Fernandez-Munoz, Rafael ;

Lozano, Rafael ;

Capel, Juan .

THEORETICAL AND APPLIED GENETICS, 2017, 130 (05) :903-913

[7]

Multi-environment QTL mapping reveals genetic architecture of fruit cracking in a tomato RIL Solanum lycopersicum x S-pimpinellifolium population [J].

Capel, Carmen ;

Yuste-Lisbona, Fernando J. ;

Lopez-Casado, Gloria ;

Angosto, Trinidad ;

Cuartero, Jesus ;

Lozano, Rafael ;

Capel, Juan .

THEORETICAL AND APPLIED GENETICS, 2017, 130 (01) :213-222

[8]

Integrated analysis of metabolite and transcript levels reveals the metabolic shifts that underlie tomato fruit development and highlight regulatory aspects of metabolic network behavior [J].

Carrari, Fernando ;

Baxter, Charles ;

Usadel, Bjorn ;

Urbanczyk-Wochniak, Ewa ;

Zanor, Maria-Ines ;

Nunes-Nesi, Adriano ;

Nikiforova, Victoria ;

Centero, Danilo ;

Ratzka, Antje ;

Pauly, Markus ;

Sweetlove, Lee j ;

Fernie, Alisdair R. .

PLANT PHYSIOLOGY, 2006, 142 (04) :1380-1396

[9]

Marker-assisted selection: an approach for precision plant breeding in the twenty-first century [J].

Collard, Bertrand C. Y. ;

Mackill, David J. .

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2008, 363 (1491) :557-572

[10]

Identification of Genes in the Phenylalanine Metabolic Pathway by Ectopic Expression of a MYB Transcription Factor in Tomato Fruit [J].

Dal Cin, Valeriano ;

Tieman, Denise M. ;

Tohge, Takayuki ;

McQuinn, Ryan ;

de Vos, Ric C. H. ;

Osorio, Sonia ;

Schmelz, Eric A. ;

Taylor, Mark G. ;

Smits-Kroon, Miriam T. ;

Schuurink, Robert C. ;

Haring, Michel A. ;

Giovannoni, James ;

Fernie, Alisdair R. ;

Klee, Harry J. .

PLANT CELL, 2011, 23 (07) :2738-2753

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