Cloning and biochemical characterization of a class A β-lactamase from Prevotella intermedia

被引：39

作者：

Madinier, I

Fosse, T

Giudicelli, J

Labia, R

机构：

[1] Hop Archet 2, Bacteriol Lab, F-06202 Nice 3, France

[2] Fac Chirurg Dentaire, Lab Pathobiol Orale, F-06357 Nice, France

[3] Fac Med, Biochim Lab, INSERM 145, F-06107 Nice 2, France

[4] CNRS, UMR 175, F-29000 Quimper, France

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 08期

关键词：

D O I：

10.1128/AAC.45.8.2386-2389.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The gene encoding a B-lactamase of Prevotella intermedia was cloned and sequenced. This gene, called cfxA2, shared 98% identity with cfxA, the structural gene of a beta -lactamase previously described in Bacteroides vulgatus. The deduced protein sequence had a K272E substitution. CfxA2 had the characteristics of class A, group 2e beta -lactamases.

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页码：2386 / 2389

页数：4

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