Multifunctional Nanoparticles for Dual Imaging

被引：101

作者：

Ali, Z. ^{[1
,2
]}

Abbasi, A. Z. ^{[1
,2
]}

Zhang, F. ^{[1
,2
]}

Arosio, P. ^{[4
,5
]}

Lascialfari, A. ^{[4
,5
,6
,7
]}

Casula, M. F. ^{[8
,9
]}

Wenk, A. ^{[10
]}

Kreyling, W. ^{[10
]}

Plapper, R. ^{[11
]}

Seidel, M. ^{[11
]}

Niessner, R. ^{[11
]}

Knoell, J. ^{[3
]}

Seubert, A. ^{[3
]}

Parak, W. J. ^{[1
,2
]}

机构：

[1] Univ Marburg, Fachbereich Phys, D-3550 Marburg, Germany

[2] Univ Marburg, Wissensch Zentrum Mat Wissensch, D-3550 Marburg, Germany

[3] Univ Marburg, Fachbereich Chem, D-3550 Marburg, Germany

[4] Univ Milan, Dipartimento Sci Mol Applicate Biosistemi, Milan, Italy

[5] CNR Ist Nanosci, Modena, Italy

[6] Univ Pavia, Dipartimento Fis A Volta, I-27100 Pavia, Italy

[7] Univ Pavia, INSTM, I-27100 Pavia, Italy

[8] Univ Cagliari, Dipartimento Sci Chim, Monserrato, Italy

[9] Univ Cagliari, INSTM, Monserrato, Italy

[10] Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Lung Biol & Dis, Comprehens Pneumol Ctr, Neuherberg, Germany

[11] Tech Univ Munich, Inst Hydrochem, Munich, Germany

来源：

ANALYTICAL CHEMISTRY | 2011年 / 83卷 / 08期

关键词：

POSITRON-EMISSION-TOMOGRAPHY; IN-VIVO; QUANTUM DOTS; MAGNETIC NANOPARTICLES; AMPHIPHILIC POLYMER; INORGANIC NANOPARTICLES; COLLOIDAL NANOPARTICLES; FLUORESCENCE; NANOCRYSTALS; VITRO;

D O I：

10.1021/ac103261y

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

For imaging with different modalities, labels, which provide contrast for all modalities, are required. Colloidal nanoparticles composed out of an inorganic core and a polymer shell offer progress in this direction. Both, the core and the polymer shell, can be synthesized to be fluorescent, magnetic, or radioactive. When different cores are combined with different polymer shells, different types of particles for dual imaging can be obtained, as for example, fluorescent cores with radioactive polymer shells. Properties and perspectives of such nanoparticles for multimodal imaging are discussed.

引用

页码：2877 / 2882

页数：6

共 83 条

[1] Near-Infrared Emitting Fluorophore-Doped Calcium Phosphate Nanoparticles for In Vivo Imaging of Human Breast Cancer [J].

Altinoglu, Erhan i. ;

Russin, Timothy J. ;

Kaiser, James M. ;

Barth, Brian M. ;

Eklund, Peter C. ;

Kester, Mark ;

Adair, James H. .

ACS NANO, 2008, 2 (10) :2075-2084

[2]

[Anonymous], 2010, NANOTECHNOLOGY, V21

[3] Noninvasive imaging of quantum dots in mice [J].

Ballou, B ;

Lagerholm, BC ;

Ernst, LA ;

Bruchez, MP ;

Waggoner, AS .

BIOCONJUGATE CHEMISTRY, 2004, 15 (01) :79-86

[4] E-Textile Conductors and Polymer Composites for Conformal Lightweight Antennas [J].

Bayram, Yakup ;

Zhou, Yijun ;

Shim, Bong Sup ;

Xu, Shimei ;

Zhu, Jian ;

Kotov, Nick A. ;

Volakis, John L. .

IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION, 2010, 58 (08) :2732-2736

[5] Peptide Nucleic Acid Films and Capsules: Assembly and Enzymatic Degradation [J].

Becker, Alisa L. ;

Johnston, Angus P. R. ;

Caruso, Frank .

MACROMOLECULAR BIOSCIENCE, 2010, 10 (05) :488-495

[6] Fluorescence-modified superparamagnetic nanoparticles:: Intracellular uptake and use in cellular imaging [J].

Bertorelle, Franck ;

Wilhelm, Claire ;

Roger, Jacky ;

Gazeau, Florence ;

Menager, Christine ;

Cabuil, Valerie .

LANGMUIR, 2006, 22 (12) :5385-5391

[7] Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging [J].

Bhaskar, Sonu ;

Tian, Furong ;

Stoeger, Tobias ;

Kreyling, Wolfgang ;

de la Fuente, Jesus M. ;

Grazu, Valeria ;

Borm, Paul ;

Estrada, Giovani ;

Ntziachristos, Vasilis ;

Razansky, Daniel .

PARTICLE AND FIBRE TOXICOLOGY, 2010, 7

[8]

Bombardieri E, 2010, Q J NUCL MED MOL IM, V54, P3

[9] Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature [J].

Cai, Weibo ;

Chen, Kai ;

Li, Zi-Bo ;

Gambhir, Sanjiv S. ;

Chen, Xiaoyuan .

JOURNAL OF NUCLEAR MEDICINE, 2007, 48 (11) :1862-1870

[10] Synergistically Integrated Nanoparticles as Multimodal Probes for Nanobiotechnology [J].

Cheon, Jinwoo ;

Lee, Jae-Hyun .

ACCOUNTS OF CHEMICAL RESEARCH, 2008, 41 (12) :1630-1640

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