Enantioselective synthesis of (3R,6S,7R,18R,19S)-, (3R,6S,7R,18R,19R)-, and (3R,6S,7R,18S,19R)-quassiols A. A comment on the stereochemistry of natural quassiol A

被引：16

作者：

Kodama, M

Yoshio, S

Tabata, T

Deguchi, Y

Sekiya, Y

Fukuyama, Y

机构：

[1] Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770, Yamashiro-cho

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 26期

关键词：

D O I：

10.1016/S0040-4039(97)00992-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(3R,6S,7R,18R,19S)-, (3R,6S,7R,18R,19R)-, and (3R,6S,7R,18S,19R)- Quassiols A were synthesized enantioselectively by using baker's yeast reduction and asymmetric dihydroxylation, but their optical properties were not identical to that of natural quassiol A. Stereostructure of natural quassiol A was proposed. (C) 1997 Elsevier Science Ltd.

引用

页码：4627 / 4630

页数：4

共 9 条

[1]

KODAMA M, 1990, TETRAHEDRON LETT, V31, P4025

[2] DETERMINATION OF THE ABSOLUTE-CONFIGURATION OF ORGANIC-COMPOUNDS BY MEANS OF NMR-SPECTROSCOPY - MODIFIED MOSHER METHOD [J].