Pd-catalyzed asymmetric allylation with a novel C2-symmetric bisphosphinite ligand:: 3R,3′R-bis(diphenylphosphinoxy)-6,6,6′,6′-tetramethyl-2S,2′S-di-4H-pyran

被引：9

作者：

Zhang, RZ ^{[1
]}

Yu, LB ^{[1
]}

Xu, L ^{[1
]}

Wang, ZQ ^{[1
]}

Ding, KL ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 43期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/S0040-4039(01)01624-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel C-2-symmetric chiral bisphosphinite ligand, 3R,3'R-bis(diphenylphosphinoxy)-6,6,6',6'-tetramethyl-2S,2'S-di-4H-pyran, was synthesized from D-mannitol and examined for palladium-catalyzed asymmetric allylic substitution. Under the optimized conditions, the allylation product can be obtained in up to 91.2% ee. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：7659 / 7662

页数：4

共 19 条

[1] Novel spiro phosphinite ligands and their application in homogeneous catalytic hydrogenation reactions [J].