Target mimics modulate miRNAs

被引：38

作者：

Chitwood, Daniel H. ^{[1
]}

Timmermans, Marja C. P. ^{[1
]}

机构：

[1] Cold Spring Harbor Lab, Watson Sch Biol Sci, Cold Spring Harbor, NY 11724 USA

来源：

NATURE GENETICS | 2007年 / 39卷 / 08期

关键词：

D O I：

10.1038/ng0807-935

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A 23-nucleotide sequence conserved in species from rice to Arabidopsis thaliana in a family of noncoding RNAs resembles a cleavable miRNA target site—but not exactly. A new study demonstrates that the site is not cleaved and instead negatively regulates miRNA activity through mimicry.

引用

页码：935 / 936

页数：2

共 13 条

[1] Phosphate sensing in higher plants [J].

Abel, S ;

Ticconi, CA ;

Delatorre, CA .

PHYSIOLOGIA PLANTARUM, 2002, 115 (01) :1-8

[2] pho2, a phosphate overaccumulator, is caused by a nonsense mutation in a MicroRNA399 target gene [J].

Aung, Kyaw ;

Lin, Shu-I ;

Wu, Chia-Chune ;

Huang, Yu-Ting ;

Su, Chun-Lin ;

Chiou, Tzyy-Jen .

PLANT PHYSIOLOGY, 2006, 141 (03) :1000-1011

[3] A two-hit trigger for siRNA biogenesis in plants [J].

Axtell, Michael J. ;

Jan, Calvin ;

Rajagopalan, Ramya ;

Bartel, David P. .

CELL, 2006, 127 (03) :565-577

[4] PHO2, microRNA399, and PHR1 define a phosphate-signaling pathway in plants [J].

Bari, Rajendra ;

Pant, Bikram Datt ;

Stitt, Mark ;

Scheible, Wolf-Ruediger .

PLANT PHYSIOLOGY, 2006, 141 (03) :988-999

[5] A novel gene whose expression in Medicago truncatula roots is suppressed in response to colonization by vesicular-arbuscular mycorrhizal (VAM) fungi and to phosphate nutrition [J].

Burleigh, SH ;

Harrison, MJ .

PLANT MOLECULAR BIOLOGY, 1997, 34 (02) :199-208

[6] Regulation of phosphate homeostasis by microRNA in Arabidopsis [J].

Chiou, TJ ;

Aung, K ;

Lin, SI ;

Wu, CC ;

Chiang, SF ;

Su, CL .

PLANT CELL, 2006, 18 (02) :412-421

[7] The role of microRNAs in sensing nutrient stress [J].

Chiou, Tzyy-Jen .

PLANT CELL AND ENVIRONMENT, 2007, 30 (03) :323-332

[8] Target mimicry provides a new mechanism for regulation of microRNA activity [J].

Franco-Zorrilla, Jose Manuel ;

Valli, Adrian ;

Todesco, Marco ;

Mateos, Isabel ;

Puga, Maria Isabel ;

Rubio-Somoza, Ignacio ;

Leyva, Antonio ;

Weigel, Detlef ;

Garcia, Juan Antonio ;

Paz-Ares, Javier .

NATURE GENETICS, 2007, 39 (08) :1033-1037

[9] A miRNA involved in phosphate-starvation response in Arabidopsis [J].

Fujii, H ;

Chiou, TJ ;

Lin, SI ;

Aung, K ;

Zhu, JK .

CURRENT BIOLOGY, 2005, 15 (22) :2038-2043

[10] Differential expression of TPS11, a phosphate starvation-induced gene in tomato [J].

Liu, CM ;

Muchhal, US ;

Raghothama, KG .

PLANT MOLECULAR BIOLOGY, 1997, 33 (05) :867-874

← 1 2 →