bone marrow;
mesenchymal stem cell;
cardiomyocytes;
regenerative medicine;
D O I:
10.1038/sj.bmt.1703940
中图分类号:
Q6 [生物物理学];
学科分类号:
071011 ;
摘要:
Bone marrow cells have been suggested to have multilineage plasticity including formation of cardiac tissue. We have established a cardiomyogenic (CMG) cell line from mouse bone marrow stromal cells that can be induced to differentiate into cardiomyocytes in vitro by 5-azacytidine treatment. A number of lines of evidence confirm the cardiomyocyte characteristics of CMG cells.