Use of adult marrow mesenchymal stem cells for regeneration of cardiomyocytes

被引:57
作者
Fukuda, K [1 ]
机构
[1] Keio Univ, Sch Med, Inst Adv Cardiac Therapeut, Shinjuku Ku, Tokyo 1608582, Japan
关键词
bone marrow; mesenchymal stem cell; cardiomyocytes; regenerative medicine;
D O I
10.1038/sj.bmt.1703940
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Bone marrow cells have been suggested to have multilineage plasticity including formation of cardiac tissue. We have established a cardiomyogenic (CMG) cell line from mouse bone marrow stromal cells that can be induced to differentiate into cardiomyocytes in vitro by 5-azacytidine treatment. A number of lines of evidence confirm the cardiomyocyte characteristics of CMG cells.
引用
收藏
页码:S25 / S27
页数:3
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