Orexin/hypocretin: Wired for wakefulness

被引:15
作者
Mochizuki, T [1 ]
Scammell, TE [1 ]
机构
[1] Beth Israel Deaconess Med Ctr, Dept Neurol, Boston, MA 02215 USA
关键词
D O I
10.1016/S0960-9822(03)00474-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Orexin neurons play a crucial role in regulating wakefulness and energy metabolism, but until recently, little was known about the factors that influence the activity of these essential cells. Electrophysiological studies have now identified positive and negative feedback signals that allow the orexin neurons to help maintain wakefulness.
引用
收藏
页码:R563 / R564
页数:2
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