No Superoxide-No Stress? Nox4, the Good NADPH Oxidase!

被引：38

作者：

Brandes, Ralf P. ^{[1
]}

Takac, Ina ^{[1
]}

Schroeder, Katrin ^{[1
]}

机构：

[1] Goethe Univ Frankfurt, Fachbereich Med, Inst Kardiovaskulare Physiol, D-60590 Frankfurt, Germany

来源：

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY | 2011年 / 31卷 / 06期

关键词：

endothelial function; endothelium; hypertension; nitric oxide; reactive oxygen species; OXIDATIVE STRESS; ANGIOTENSIN-II; DISEASE;

D O I：

10.1161/ATVBAHA.111.226894

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：1255 / 1257

页数：3

共 14 条

[1] Endothelial Nox2 overexpression potentiates vascular oxidative stress and hemodynamic response to angiotensin II - Studies in endothelial-targeted Nox2 transgenic mice [J].

Bendall, Jennifer K. ;

Rinze, Ruth ;

Adlam, David ;

Tatham, Amy L. ;

de Bono, Joe ;

Channon, Keith M. .

CIRCULATION RESEARCH, 2007, 100 (07) :1016-1025

[2] NADPH oxidases in cardiovascular disease [J].

Brandes, Ralf P. ;

Weissmann, Norbert ;

Schroder, Katrin .

FREE RADICAL BIOLOGY AND MEDICINE, 2010, 49 (05) :687-706

[3] Hydrogen peroxide regulation of endothelial function: Origins, mechanisms, and consequences [J].

Cai, H .

CARDIOVASCULAR RESEARCH, 2005, 68 (01) :26-36

[4]

Carnesecchi S., 2011, ANTIOXID REDOX SIGNA

[5] Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling [J].

Dikalova, Anna E. ;

Gongora, Maria Carolina ;

Harrison, David G. ;

Lambeth, J. David ;

Dikalov, Sergey ;

Griendling, Kathy K. .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2010, 299 (03) :H673-H679

[6] Analysis of DHE-derived oxidation products by HPLC in the assessment of superoxide production and NADPH oxidase activity in vascular systems [J].

Fernandes, Denise C. ;

Wosniak, Joao, Jr. ;

Pescatore, Luciana A. ;

Bertoline, Maria A. ;

Liberman, Marcel ;

Laurindo, Francisco R. M. ;

Santos, Celio X. C. .

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2007, 292 (01) :C413-C422

[7] Janus-faced role of endothelial NO synthase in vascular disease:: uncoupling of oxygen reduction from NO synthesis and its pharmacological reversal [J].

Foerstermann, Ulrich .

BIOLOGICAL CHEMISTRY, 2006, 387 (12) :1521-1533

[8] ANGIOTENSIN-II STIMULATES NADH AND NADPH OXIDASE ACTIVITY IN CULTURED VASCULAR SMOOTH-MUSCLE CELLS [J].

GRIENDLING, KK ;

MINIERI, CA ;

OLLERENSHAW, JD ;

ALEXANDER, RW .

CIRCULATION RESEARCH, 1994, 74 (06) :1141-1148

[9] NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart [J].

Kuroda, Junya ;

Ago, Tetsuro ;

Matsushima, Shouji ;

Zhai, Peiyong ;

Schneider, Michael D. ;

Sadoshima, Junichi .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (35) :15565-15570

[10] Novel Nox homologues in the vasculature: focusing on Nox4 and Nox5 [J].

Montezano, Augusto C. ;

Burger, Dylan ;

Ceravolo, Graziela S. ;

Yusuf, Hiba ;

Montero, Maria ;

Touyz, Rhian M. .

CLINICAL SCIENCE, 2011, 120 (3-4) :131-141

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