IFI60/ISG60/IFIT4, a new member of the human IFI54/IFIT2 family of interferon-stimulated genes

被引：57

作者：

de Veer, MJ ^{[1
]}

Sim, H ^{[1
]}

Whisstock, JC ^{[1
]}

Devenish, RJ ^{[1
]}

Ralph, SJ ^{[1
]}

机构：

[1] Monash Univ, Dept Biochem & Mol Biol, Clayton, Vic 3168, Australia

来源：

GENOMICS | 1998年 / 54卷 / 02期

关键词：

D O I：

10.1006/geno.1998.5555

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We report the cloning and sequencing of a full-length cDNA encoding a new member of the human IFI54 (HGMW-approved symbol IFIT2) gene family, designated IFI60 (HGMW-approved symbol IFIT4). The upstream regulatory region of IFI60 shows conservation in structure with that of the IFI54 and IFI56 (HGMW-approved symbol IFIT1) genes, each containing two interferon-stimulated response elements upstream of a conserved TATA box. We have established a partial gene map of the IFI54 gene family by analysis of YAC library clones. All four members of the human family are clustered together at chromosome 10q23.3. It is proposed that the four members of the IFI54 gene family evolved by a series of duplication events from a common gene of origin. (C) 1998 Academic Press.

引用

页码：267 / 277

页数：11

共 47 条

[1] SEQUENCE IDENTIFICATION OF 2,375 HUMAN BRAIN GENES
ADAMS, MD
DUBNICK, M
KERLAVAGE, AR
MORENO, R
KELLEY, JM
UTTERBACK, TR
NAGLE, JW
FIELDS, C
VENTER, JC
[J]. NATURE, 1992, 355 (6361) : 632 - 634
[2] CONSTRUCTION AND CHARACTERIZATION OF A YEAST ARTIFICIAL CHROMOSOME LIBRARY CONTAINING 7 HAPLOID HUMAN GENOME EQUIVALENTS
ALBERTSEN, HM
ABDERRAHIM, H
CANN, HM
DAUSSET, J
LEPASLIER, D
COHEN, D
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (11) : 4256 - 4260
[3] BASIC LOCAL ALIGNMENT SEARCH TOOL
ALTSCHUL, SF
GISH, W
MILLER, W
MYERS, EW
LIPMAN, DJ
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1990, 215 (03) : 403 - 410
[4] IMMUNOSUPPRESSION BY GLUCOCORTICOIDS - INHIBITION OF NF-KAPPA-B ACTIVITY THROUGH INDUCTION OF I-KAPPA-B SYNTHESIS
AUPHAN, N
DIDONATO, JA
ROSETTE, C
HELMBERG, A
KARIN, M
[J]. SCIENCE, 1995, 270 (5234) : 286 - 290
[5] Baker E, 1997, Chromosome Res, V5, P572
[6] ALSCRIPT - A TOOL TO FORMAT MULTIPLE SEQUENCE ALIGNMENTS
BARTON, GJ
[J]. PROTEIN ENGINEERING, 1993, 6 (01): : 37 - 40
[7] Beetz A, 1997, INT J RADIAT BIOL, V72, P33, DOI 10.1080/095530097143518
[8] BERTLING WM, 1993, PCR METH APPL, V3, P95
[9] THE INTERFERON-STIMULATED GENE 54 K PROMOTER CONTAINS 2 ADJACENT FUNCTIONAL INTERFERON-STIMULATED RESPONSE ELEMENTS OF DIFFERENT STRENGTH, WHICH ACT SYNERGISTICALLY FOR MAXIMAL INTERFERON-ALPHA INDUCIBILITY
BLUYSSEN, HAR
VLIETSTRA, RJ
VANDERMADE, A
TRAPMAN, J
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1994, 220 (02): : 395 - 402
[10] STRUCTURE, CHROMOSOME LOCALIZATION, AND REGULATION OF EXPRESSION OF THE INTERFERON-REGULATED MOUSE IFI54/IFI56 GENE FAMILY
BLUYSSEN, HAR
VLIETSTRA, RJ
FABER, PW
SMIT, EME
HAGEMEIJER, A
TRAPMAN, J
[J]. GENOMICS, 1994, 24 (01) : 137 - 148

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