Molecular and cellular mechanisms of action of angiotensin II (AT1) receptors in vascular smooth muscle

被引:23
作者
Hughes, AD [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, London W2 1NY, England
关键词
angiotensin II; signal transduction; ion channels; vascular smooth muscle;
D O I
10.1038/sj.jhh.1000635
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Angiotensin is an important regulator of blood pressure and exerts both presser actions and influences growth in the cardiovascular system via the AT(1 )receptor. This review describes a number of signalling mechanisms involved in vasoconstriction and growth in response to AT(1) receptor activation in vascular smooth muscle.
引用
收藏
页码:275 / 281
页数:7
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