Assessment of glioma proliferation using imaging modalities

被引:52
作者
Alexiou, George A. [1 ]
Tsiouris, Spyridon [2 ]
Kyritsis, Athanasios P. [3 ]
Argyropoulou, Maria I. [4 ]
Voulgaris, Spyridon [1 ]
Fotopoulos, Andreas D. [2 ]
机构
[1] Univ Hosp Ioannina, Dept Neurosurg, Ioannina 45110, Greece
[2] Univ Hosp Ioannina, Dept Nucl Med, Ioannina 45110, Greece
[3] Univ Hosp Ioannina, Dept Neurol, Ioannina 45110, Greece
[4] Univ Hosp Ioannina, Dept Radiol, Ioannina 45110, Greece
关键词
Glioma; MRI; PET; Proliferation; SPECT; POSITRON-EMISSION-TOMOGRAPHY; CELL NUCLEAR ANTIGEN; PROTON MR SPECTROSCOPY; KI-67 LABELING INDEX; PRIMARY BRAIN-TUMORS; IN-VIVO; RESONANCE SPECTROSCOPY; ASTROCYTIC TUMORS; PROGNOSTIC-SIGNIFICANCE; TC-99M-(V)-DMSA UPTAKE;
D O I
10.1016/j.jocn.2010.03.021
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
The assessment of glioma proliferation rate is important to predict tumor behavior, response to therapy and prognosis. Various methods, largely involving immunohistological markers in tissue samples, have been proposed to this aim; however, they all require tissue removal through a biopsy or during a surgical procedure. Consequently, non-invasive imaging modalities that could reliably assess the proliferative potential of intracranial space-occupying lesions in vivo would be of obvious significance. In the present study we review the contribution of MRI, positron emission tomography and single-photon emission CT for the assessment of the proliferative potential of gliomas. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1233 / 1238
页数:6
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