MASIC: A software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC-MS(/MS) features

被引：125

作者：

Monroe, Matthew E. ^{[1
]}

Shaw, Jason L. ^{[1
]}

Daly, Don S. ^{[1
]}

Adkins, Joshua N. ^{[1
]}

Smith, Richard D. ^{[1
]}

机构：

[1] Pacific NW Natl Lab, Richland, WA 99354 USA

来源：

COMPUTATIONAL BIOLOGY AND CHEMISTRY | 2008年 / 32卷 / 03期

关键词：

liquid chromatography-tandem mass; spectrometry (LC-MS/MS); quantitation; proteomics; quantification; selected ion chromatogram;

D O I：

10.1016/j.compbiolchem.2008.02.006

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Quantitative analysis of liquid chromatography (LC)-mass spectrometry (MS) and tandem mass spectrometry (MS/MS) data is essential to many proteomics studies. We have developed MASIC(2) to accurately measure peptide abundances and LC elution times in LC-MS/MS analyses. This software program uses an efficient processing algorithm to quickly generate mass specific selected ion chromatograms from a dataset and provides an interactive browser that allows users to examine individual chromatograms with a variety of options. (C) 2008 Elsevier Ltd. All rights reserved.

引用

收藏

页码：215 / 217

页数：3

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