Ruthenium-catalyzed asymmetric reduction of 1,3-diketones using transfer hydrogenation

被引：65

作者：

Cossy, J ^{[1
]}

Eustache, F ^{[1
]}

Dalko, PI ^{[1
]}

机构：

[1] Ecole Super Phys & Chim Ind, Chim Organ Lab, F-75231 Paris 05, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 30期

关键词：

1,3-diketones; 1,3-diols; reduction; ruthenium; catalyst;

D O I：

10.1016/S0040-4039(01)00906-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,3-Diketones were reduced to 1.3-diols by using RuCl[N-(tosyl)-1,2-(diphenylethylenediamine) (eta (6)-arene)] in the presence of formic acid and triethylamine. 1.3-Diols were obtained in good chemical yields and with high ee when symmetrical diketones were reduced. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：5005 / 5007

页数：3

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