Palladium-catalyzed α-arylation of aldehydes with bromo- and chloroarenes catalyzed by [{Pd(allyl)Cl}2] and dppf or Q-phos

被引：106

作者：

Vo, Giang D. ^{[1
]}

Hartwig, John E. ^{[1
]}

机构：

[1] Univ Illinois, Dept Chem, Urbana, IL 61801 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 11期

关键词：

aldehydes; arylation; cross-coupling; palladium;

D O I：

10.1002/anie.200705357

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Pd source matters: A general method for palladium-catalyzed a-arylation of aldehydes (see scheme) was developed to couple linear and branched aldehydes with electron-poor and electron-rich bromo- and chloroarenes. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2127 / 2130

页数：4

共 27 条

[1] Palladium-catalyzed arylation of malonates and cyanoesters using sterically hindered trialkyl- and ferrocenyldialkylphosphine ligands
Beare, NA
Hartwig, JF
[J]. JOURNAL OF ORGANIC CHEMISTRY, 2002, 67 (02) : 541 - 555
[2] Palladium-catalyzed α-arylation of carbonyl compounds and nitriles
Culkin, DA
Hartwig, JF
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 2003, 36 (04) : 234 - 245
[3] Total synthesis of spirotryprostatin A, leading to the discovery of some biologically promising analogues
Edmondson, S
Danishefsky, SJ
Sepp-Lorenzino, L
Rosen, N
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (10) : 2147 - 2155
[4] Ehrentraut A, 2002, ADV SYNTH CATAL, V344, P209, DOI 10.1002/1615-4169(200202)344:2<209::AID-ADSC209>3.0.CO
[5] 2-5
[6] Highly active and selective catalysts for the formation of α-aryl ketones
Fox, JM
Huang, XH
Chieffi, A
Buchwald, SL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (07) : 1360 - 1370
[7] Palladium-catalyzed intermolecular α-arylation of zinc amide enolates under mild conditions
Hama, T
Culkin, DA
Hartwig, JF
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (15) : 4976 - 4985
[8] Palladium-catalyzed α-arylation of esters and amides under more neutral conditions
Hama, T
Liu, XX
Culkin, DA
Hartwig, JF
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (37) : 11176 - 11177
[9] Catalytic asymmetric reductive amination of aldehydes via dynamic kinetic resolution
Hoffmann, Sebastian
Nicoletti, Marcello
List, Benjamin
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (40) : 13074 - 13075
[10] Air stable, sterically hindered ferrocenyl dialkylphosphines for palladium-catalyzed C-C, C-N, and C-O bond-forming cross-couplings
Kataoka, N
Shelby, Q
Stambuli, JP
Hartwig, JF
[J]. JOURNAL OF ORGANIC CHEMISTRY, 2002, 67 (16) : 5553 - 5566

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