Cobalt-Catalyzed Preparation of Arylindium Reagents from Aryl and Heteroaryl Bromides

被引：39

作者：

Adak, Laksmikanta ^{[1
]}

Yoshikai, Naohiko ^{[1
]}

机构：

[1] Nanyang Technol Univ, Div Chem & Biol Chem, Sch Phys & Math Sci, Singapore 637371, Singapore

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 76卷 / 18期

基金：

新加坡国家研究基金会;

关键词：

CROSS-COUPLING REACTIONS; INDIUM ORGANOMETALLICS; TRIORGANOINDIUM COMPOUNDS; FUNCTIONALIZED ARYLZINC; ORGANOZINC COMPOUNDS; ORGANIC-SYNTHESIS; DIRECT INSERTION; MILD CONDITIONS; AQUEOUS-MEDIA; ZINC DUST;

D O I：

10.1021/jo201174r

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A cobalt bathophenanthroline catalyst has been developed for the direct preparation of a variety of arylindium reagents from the corresponding aryl and heteroaryl bromides in the presence of indium metal and lithium chloride. The thus-formed arylindium reagents undergo efficient palladium-catalyzed cross-coupling reactions with aryl iodides, tolerating various functional groups including hydroxy and free amino groups.

引用

页码：7563 / 7568

页数：6

共 46 条

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