Large discrete transition in a single DNA molecule appears continuous in the ensemble

被引：272

作者：

Yoshikawa, K

Takahashi, M

Vasilevskaya, VV

Khokhlov, AR

机构：

[1] RUSSIAN ACAD SCI,AN NESMEYANOV ORGANOELEMENT CPDS INST,MOSCOW 117813,RUSSIA

[2] MOSCOW MV LOMONOSOV STATE UNIV,DEPT PHYS,MOSCOW 117234,RUSSIA

来源：

PHYSICAL REVIEW LETTERS | 1996年 / 76卷 / 16期

关键词：

D O I：

10.1103/PhysRevLett.76.3029

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We observed giant double-stranded DNA chains by fluorescence microscopy in an aqueous environment. We found that the coil-globule transition of T4DNA, 166kbp, induced by spermidine is markedly discrete for individual chains, and continuous for their ensemble average. Simple theoretical consideration is given taking account of the hierarchy of the system. It is suggested that the unique characteristics of the transition for long DNA has a general significance for the coil-globule transition in other biological and synthetic ''stiff polymers.''

引用

页码：3029 / 3031

页数：3

共 18 条

[11] THEORY OF DNA CONDENSATION - COLLAPSE VERSUS AGGREGATION [J].