A simple and direct method for converting thioamides into thioesters

被引：30

作者：

Harrowven, DC ^{[1
]}

Lucas, MC

Howes, PD

机构：

[1] Univ Southampton, Dept Chem, Southampton SO17 1BJ, Hants, England

[2] Glaxo Wellcome Res & Dev Ltd, Med Res Ctr, Stevenage SG1 2NY, Herts, England

来源：

TETRAHEDRON | 1999年 / 55卷 / 04期

关键词：

thioester; thioamide; alkylation;

D O I：

10.1016/S0040-4020(98)01096-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Thioamides may be transformed into thioesters through the simple expedient of warming them in an aqueous THF solution containing an alkylating agent. Reactions proceed in high yield and are amenable to multi-gram scale. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1187 / 1196

页数：10

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