Enteric Viruses in a Large Waterborne Outbreak of Acute Gastroenteritis in Finland

被引：55

作者：

Maunula, L. ^{[1
]}

Klemola, P. ^{[2
]}

Kauppinen, A. ^{[2
]}

Soderberg, K. ^{[1
]}

Nguyen, T. ^{[2
]}

Pitkanen, T. ^{[2
]}

Kaijalainen, S. ^{[2
]}

Simonen, M. L. ^{[2
]}

Miettinen, I. T. ^{[2
]}

Lappalainen, M. ^{[3
]}

Laine, J. ^{[2
]}

Vuento, R. ^{[4
]}

Kuusi, M. ^{[2
]}

Roivainen, M. ^{[2
]}

机构：

[1] Univ Helsinki, Fac Vet Med, Dept Food & Environm Hyg, FIN-00014 Helsinki, Finland

[2] Natl Publ Hlth Inst, Kuopio, Finland

[3] Univ Helsinki, Cent Hosp, Dept Virol, Lab Div HUSLAB, FIN-00014 Helsinki, Finland

[4] Tampere Univ Hosp, Ctr Lab Med, Tampere, Finland

来源：

FOOD AND ENVIRONMENTAL VIROLOGY | 2009年 / 1卷 / 01期

关键词：

RT-PCR; Real-time RT-PCR; Enteric viruses; Norovirus; Astrovirus; Rotavirus; Enterovirus; Adenovirus; Hepatitis A virus; Waterborne outbreak; REVERSE TRANSCRIPTION-PCR; HEPATITIS-A VIRUS; TIME RT-PCR; NOROVIRUS OUTBREAKS; SENSITIVE DETECTION; ASSAY; ROTAVIRUS; QUANTIFICATION; INFECTION; SHELLFISH;

D O I：

10.1007/s12560-008-9004-3

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

In Nokia city about 450,000 l of treated sewage water was for 2 days allowed to run into the drinking water supplies of the city due to a personal error of one employee. Within the next 5 weeks about 1,000 people sought care at the municipal health centre or regional hospital because of gastroenteritis. Here we report the results of viral analyses performed by gene amplification assays from the earliest water and sewage samples as well as from close to 300 patient samples. The contaminating treated sewage was shown to harbour several enteric viruses known to cause acute gastroenteritis. Likewise, the drinking water sample was positive for noro-, astro-, rota-, entero- and adenoviruses. Noroviruses were also found in 29.8% of stool samples from affected patients, while astro-, adeno-, rota- and enteroviruses were detected in 19.7, 18.2, 7.5 and 3.7% of the specimens, respectively.

引用

页码：31 / 36

页数：6