Synthesis and application of some: New thienopyrimidine derivatives as antimicrobial agents

被引：41

作者：

Hozien, ZA

Atta, FM

Hassan, KM

AbdelWahab, AA

Ahmed, SA

机构：

[1] Department of Chemistry, Faculty of Science, Assiut University, Assiut

来源：

SYNTHETIC COMMUNICATIONS | 1996年 / 26卷 / 20期

关键词：

D O I：

10.1080/00397919608003791

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The paper describes the synthesis of new ring system 5-phenylthieno[2,3-d]pyrimidine-4(3H)one (2) Chlorination of (2) with PCl5, POCl3 gave the corresponding 4-chloro derivative (4). Several derivatives of the latter compound have been synthesised and tested for antimicrobial activity.

引用

页码：3733 / 3755

页数：23

共 15 条

[1]

Burger A., 1970, MED CHEM, V72, P544

[2]

EICHENBERGER K, 1953, Patent No. 2627766

[3]

GAWELD K, 1966, CHEM BER, V99, P94

[4] A NOVEL TETRACYCLIC RING-SYSTEM - 10H-TETRAZOLO[5',1'-3,4][1,2,4]TRIAZINO[5,6-B]INDOLE [J].