TRP channels in mechanosensation

被引:104
作者
Lin, SY
Corey, DP
机构
[1] Harvard Univ, Sch Med, Howard Hughes Med Inst, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Dept Neurobiol, Boston, MA 02115 USA
关键词
D O I
10.1016/j.conb.2005.05.012
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Channels of the TRIP superfamily have sensory roles in a wide variety of receptor cells, especially in mechanosensation. In some cases, the channels appear to be directly activated by mechanical force; in others, they appear to be downstream of a messenger pathway initiated by force on a non-channel sensor. A remaining challenge for most of these mechanosensory TRPs is to clarify the specific mechanism of activation.
引用
收藏
页码:350 / 357
页数:8
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