Oxidative access to quinolinone derivatives with simultaneous rearrangement of functional groups

被引：26

作者：

Amano, Yoshiharu ^{[1
]}

Inoue, Keisuke ^{[1
]}

Nishiyama, Shigeru ^{[1
]}

机构：

[1] Keio Univ, Dept Chem, Fac Sci & Technol, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan

来源：

SYNLETT | 2008年 / 01期

关键词：

quinolinone synthesis; oxidations; cyclizations; rearrangements; hypervalent iodine;

D O I：

10.1055/s-2007-1000829

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Hypervalent iodine-mediated oxidation of aromatic compounds carrying methoxyamide side chains provided the corresponding quinolinones. The reactive point was at the para position to electron-donating groups (such as a MeO group) in the aromatic ring. Introduction of AcO or halogen groups to this position resulted in a cyclization, concomitant with rearrangement of the functional group.

引用

页码：134 / 136

页数：3

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