Intravenous amiodarone in intensive care - Time for a reappraisal?

被引：35

作者：

Hughes, M ^{[1
]}

Binning, A

机构：

[1] Royal Infirm, Dept Anaesthet, Glasgow G31 2ER, Lanark, Scotland

[2] Univ Glasgow, Western Infirm, Dept Intens Care, Glasgow G11 6NT, Lanark, Scotland

来源：

INTENSIVE CARE MEDICINE | 2000年 / 26卷 / 12期

关键词：

amiodarone; intravenous; critical care; perioperative; outcome; atrial fibrillation; atrial tachyarrhythmias; ventricular tachyarrhythmias;

D O I：

10.1007/s001340000668

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Amiodarone is widely used in intensive care units for the treatment of a variety of arrhythmias. It is currently the drug of choice for supraventricular tachyarrhythmias in many units because of its combination of efficacy and safety. This review summarises the current state of knowledge regarding the short-term administration of intravenous amiodarone to control arrhythmias in perioperative, coronary care and intensive care patients. It outlines the electrophysiology, haemodynamics, pharmacokinetics and toxicity of the drug. In particular, it examines the recent concerns regarding acute pulmonary toxicity.

引用

页码：1730 / 1739

页数：10

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