Cascade radical cyclisations involving enamide double bonds. A synthetic approach to azasteroids

被引：13

作者：

Double, P ^{[1
]}

Pattenden, G ^{[1
]}

机构：

[1] Univ Nottingham, Dept Chem, Nottingham NG7 2RD, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1998年 / 13期

关键词：

D O I：

10.1039/a802298d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of the enamide selenoesters 8 and 14 with Bu3SnH-AIBN is shown to lead to the nitrogen tricycle 9 (63%) and the D-homo-12-azasteroid 16 (45%) respectively, by way of serial stereoselective 6-endo-trig radical cyclisations.

引用

页码：2005 / 2007

页数：3

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