Facile synthesis of highly functionalized stable ketenimines via a three-component reaction

被引：16

作者：

Alizadch, Abdolali ^{[1
]}

Rostamnia, Sadegh ^{[1
]}

机构：

[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

来源：

SYNTHESIS-STUTTGART | 2008年 / 01期

关键词：

isocyanides; oximes; ketenimines; multicomponent reactions; zwitterions;

D O I：

10.1055/s-2007-990894

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

It is shown that N-alkyl-substituted ketenimine derivatives can be efficiently prepared by the three-component coupling of electron-deficient alkynes, oximes, and isocyanides. The reaction is characterized by mild conditions, high selectivity, and tolerance to various functional groups. Yields are typically around 90%.

引用

页码：57 / 60

页数：4

共 55 条

[51] A simple and efficient approach to the synthesis of highly functionalized fused benzochromenes [J].