New hetero-annelation reactions using N-[bis-(methylthio)-methylene]-amino and related reagents

被引：19

作者：

Sauter, F

Frohlich, J

Ahmed, EK

机构：

[1] Institute of Organic Chemistry, Technical University Vienna

[2] Chemistry Department, Minia University, El-Minia

来源：

MONATSHEFTE FUR CHEMIE | 1996年 / 127卷 / 03期

关键词：

fused S; N-heterocycles; BMMA reagents; pyrimidine annelations;

D O I：

10.1007/BF00813798

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reaction of acyclic (R(1-3)) and cyclic (R(4-5)) BMMA (=N-[bis-(methylthio)-methylene]-amino) reagents with Gewald-type thiophene derivatives (2, 3) led to annelation of pyrimidine moieties. Thus, linear thiazolo- or thiazino- and pyrrolo-, pyrido- or azepino-fused thiopyrano[4',3':4,5]thieno-[2,3-d]pyrimidines (5 and 6) as well as the angular imidazo-fused thiopyrano[4,'3':4,5]thieno-[2,3-d]pyrimidine 8 were easily obtained from one-pot reactions in good yields.

引用

页码：319 / 324

页数：6

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