Cancer - Has the smart bomb been defused?

被引:10
作者
Linke, SP [1 ]
机构
[1] NCI, Human Carcinogenesis Lab, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1038/25595
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Most cancer therapies aim to destroy tumour cells, leaving the surrounding normal cells untouched. This is the basis of one treatment, involving a mutated adenovirus that is thought to destroy only those cells that lack the tumour-suppressor protein p53. But new research indicates that the adenovirus may actually require p53 to replicate, meaning that it would instead target healthy cells.
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页码:13 / +
页数:2
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