Direct arylation reactions catalyzed by Pd(OH)2/C:: Evidence for a soluble palladium catalyst

被引:293
作者
Parisien, M [1 ]
Valette, D [1 ]
Fagnou, K [1 ]
机构
[1] Univ Ottawa, Ctr Catalysis Res & Innovat, Dept Chem, Ottawa, ON K1N 6N5, Canada
关键词
D O I
10.1021/jo051039v
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Palladium hydroxide on carbon (Pearlman's catalyst) effectively catalyzes direct arylation reactions of aryl iodides and bromides, providing excellent arylation-to-hydrodehalogenation ratios (> 30:1) with broad scope for both intra- and intermolecular arylation processes. Studies aimed at determining the nature of the active catalyst indicate that an active homogeneous palladium species is produced under the reaction conditions.
引用
收藏
页码:7578 / 7584
页数:7
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