Quantitation of regional cerebral blood flow increases in prefrontal cortex during a working memory task: A steady-state arterial spin-tagging study

被引：25

作者：

Ye, FQ ^{[1
]}

Smith, AM

Mattay, VS

Ruttimann, UE

Frank, JA

Weinberger, DR

McLaughlin, AC

机构：

[1] NIMH, Clin Brain Disorders Branch, NIH, Bethesda, MD 20892 USA

[2] NIAAA, Lab Diagnost Radiol Res, OIR, NIH, Bethesda, MD 20892 USA

[3] NIAAA, Clin Studies Lab, NIH, Bethesda, MD 20892 USA

来源：

NEUROIMAGE | 1998年 / 8卷 / 01期

关键词：

D O I：

10.1006/nimg.1998.0342

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Steady-state arterial spin-tagging MRI approaches were used to quantitate regional cerebral blood flow increases in prefrontal cortex during a working memory ("two-back") task in six normal subjects. Statistically significant increases in cerebral blood flow in prefrontal cortex were observed in all six subjects: the average increase in cerebral blood flow in activated prefrontal cortex regions was 22 +/- 5 cc/100 g/min (23 +/- 7%). The results demonstrate that spin-tagging approaches can be used to follow focal activation in prefrontal cortex during cognitive tasks. (C) 1998 Academic Press.

引用

页码：44 / 49

页数：6

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