MicroParticle photophysics illuminates viral bio-sensing

被引：77

作者：

Arnold, S. ^{[1
]}

Ramjit, R. ^{[1
]}

Keng, D. ^{[1
]}

Kolchenko, V. ^{[1
]}

Teraoka, I. ^{[1
]}

机构：

[1] Polytech Univ, MicroParticle PhotoPhys Lab, Brooklyn, NY 11201 USA

来源：

FARADAY DISCUSSIONS | 2008年 / 137卷

关键词：

D O I：

10.1039/b702920a

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The authors present an approach for specific and rapid unlabeled detection of a virus by using a microsphere- based whispering gallery mode sensor that transduces the interaction of a whole virus with an anchored antibody. They show theoretically that this sensor can detect a single virion below the mass of HIV. A micro-fluidic device is presented that enables the discrimination between viruses of similar size and shape.

引用

页码：65 / 83

页数：19

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