Andropause: invention, prevention, rejuvenation

被引：36

作者：

Handelsman, DJ ^{[1
]}

Liu, PY

机构：

[1] Univ Sydney, ANZAC Res Inst, Dept Androl, Concord Hosp, Sydney, NSW 2139, Australia

[2] Mayo Clin, Endocrine Res Unit, Dept Internal Med, Div Endocrinol, Rochester, MN 55905 USA

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 2005年 / 16卷 / 02期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/j.tem.2005.01.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There is a growing interest, as well as a booming industry, in the use of testosterone therapy for middle-aged and older men. This interest has led to the definition of a new condition, termed 'andropause', meaning the putative somatic consequences of gradually failing. blood testosterone concentrations during male aging. This trend risks replicating both the rejuvenation fads of a century ago and the recent experience in estrogen therapy for menopause that has been propelled for decades by advocacy substituting for reliable scientific evidence. The current status and prospects for androgen therapy in middle-aged and older men should be evaluated critically from the perspective of male reproductive health during aging. This review appraises current knowledge with a focus on the questionable basis for using androgen therapy to improve male reproductive health during aging.

引用

页码：39 / 45

页数：7

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