Cytogenetic biomonitoring in petrol station attendants:: micronucleus test in exfoliated buccal cells

被引：107

作者：

Çelik, A ^{[1
]}

Çavas, T ^{[1
]}

Ergene-Gözükara, S ^{[1
]}

机构：

[1] Mersin Univ, Fac Sci & Lett, Dept Biol, TR-33342 Ciftlikkoy, Mersin, Turkey

来源：

MUTAGENESIS | 2003年 / 18卷 / 05期

关键词：

D O I：

10.1093/mutage/geg022

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

To study the effects of occupational exposure to petroleum derivates such as benzene, exfoliated buccal cells from 50 petrol station attendants and 50 age- and sex-matched control subjects were examined for micronucleus (MN) frequency. Frequencies of nuclear abnormalities (NA) other than micronuclei, such as binucleates, karyorrhexis and karyolysis, were also evaluated. Benzene exposure was ascertained by measuring urinary phenol levels. The mean urinary phenol level of station workers was found to be significantly higher than that of control subjects (P<0.05). Analysis of buccal cells revealed that MN and NA frequencies in petrol station workers were significantly higher than in control subjects (P<0.01) and also significantly related to smoking habit (P<0.01). Our findings indicate that the petrol station workers are under risk of significant cytogenetic damage.

引用

页码：417 / 421

页数：5

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