Graphs in molecular biology

被引：80

作者：

Huber, Wolfgang ^{[1
]}

Carey, Vincent J.

Long, Li

Falcon, Seth

Gentleman, Robert

机构：

[1] European Mol Biol Lab, European Bioinformat Inst, Cambridge CB10 1SD, England

[2] Brigham & Womens Hosp, Channing Lab, Boston, MA 02115 USA

[3] Swiss Inst Bioinformat, Vital IT Ctr, CH-1015 Lausanne, Switzerland

[4] Fred Hutchinson Canc Res Ctr, Computat Biol Grp, Seattle, WA 98109 USA

来源：

BMC BIOINFORMATICS | 2007年 / 8卷 / Suppl 6期

关键词：

D O I：

10.1186/1471-2105-8-S6-S8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Graph theoretical concepts are useful for the description and analysis of interactions and relationships in biological systems. We give a brief introduction into some of the concepts and their areas of application in molecular biology. We discuss software that is available through the Bioconductor project and present a simple example application to the integration of a protein-protein interaction and a co-expression network.

引用

页数：14

共 22 条

[1]

[Anonymous], 2000, Introduction to Graphical Modelling

[2]

[Anonymous], BOOST GRAPH LIB

[3] Gene Ontology: tool for the unification of biology [J].

Ashburner, M ;

Ball, CA ;

Blake, JA ;

Botstein, D ;

Butler, H ;

Cherry, JM ;

Davis, AP ;

Dolinski, K ;

Dwight, SS ;

Eppig, JT ;

Harris, MA ;

Hill, DP ;

Issel-Tarver, L ;

Kasarskis, A ;

Lewis, S ;

Matese, JC ;

Richardson, JE ;

Ringwald, M ;

Rubin, GM ;

Sherlock, G .

NATURE GENETICS, 2000, 25 (01) :25-29

[4] A graph-theoretic approach to testing associations between disparate sources of functional genomics data [J].

Balasubramanian, R ;

LaFramboise, T ;

Scholtens, D ;

Gentleman, R .

BIOINFORMATICS, 2004, 20 (18) :3353-3362

[5]

BERGE C, 1973, GRAPHS HYPERGRAPHS A

[6] LS SETS, LAMBDA SETS AND OTHER COHESIVE SUBSETS [J].

BORGATTI, SP ;

EVERETT, MG ;

SHIREY, PR .

SOCIAL NETWORKS, 1990, 12 (04) :337-357

[7] A genome-wide transcriptional analysis of the mitotic cell cycle [J].

Cho, RJ ;

Campbell, MJ ;

Winzeler, EA ;

Steinmetz, L ;

Conway, A ;

Wodicka, L ;

Wolfsberg, TG ;

Gabrielian, AE ;

Landsman, D ;

Lockhart, DJ ;

Davis, RW .

MOLECULAR CELL, 1998, 2 (01) :65-73

[8]

Faust K., 1994, SOCIAL NETWORK ANAL, V249

[9] DIRECTED HYPERGRAPHS AND APPLICATIONS [J].

GALLO, G ;

LONGO, G ;

PALLOTTINO, S ;

NGUYEN, S .

DISCRETE APPLIED MATHEMATICS, 1993, 42 (2-3) :177-201

[10]

Gansner ER, 2000, SOFTWARE PRACT EXPER, V30, P1203, DOI 10.1002/1097-024X(200009)30:11<1203::AID-SPE338>3.0.CO

← 1 2 3 →