Synthesis of Pt@Fe2O3 nanorods as MRI probes for in vivo application

被引:20
作者
Li, Yonggang [1 ]
Lu, Yinjie [2 ]
Hong, Haiyan [2 ]
Chen, Yinyin [1 ]
Ma, Xinxing [1 ]
Guo, Liang [1 ]
Wang, Zhongling [1 ]
Chen, Jianhua [1 ]
Zhu, Mo [1 ]
Ni, Jiankun [3 ]
Gu, Hongwei [2 ]
Lu, Jianmei [2 ]
Ying, Jackie Y. [4 ]
机构
[1] Soochow Univ, Affiliated Hosp 1, Dept Radiol, Suzhou 215006, Peoples R China
[2] Soochow Univ, Coll Chem Chem Engn & Mat Sci, Key Lab Organ Synth Jiangsu Prov, Suzhou 215123, Peoples R China
[3] First People Hosp Wujiang City, Dept Radiol, Wujiang 215200, Peoples R China
[4] Inst Bioengn & Nanotechnol, Singapore 138669, Singapore
关键词
IRON-OXIDE NANOPARTICLES; MAGNETIC NANOPARTICLES; CONTRAST; CANCER; NANOCRYSTALS; NANOWIRES;
D O I
10.1039/c1cc10758e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Magnetic Fe2O3 nanorods with low cell toxicity were successfully synthesized via a wet-chemical method. In vivo studies with a rabbit model show that the nanorods exhibit excellent T-2 signal enhancement. This work demonstrates that magnetic nanorods may provide a new type of MR enhancement agent for use in biomedical applications.
引用
收藏
页码:6320 / 6322
页数:3
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