TreeFam:: 2008 update

被引：256

作者：

Ruan, Jue ^{[2
]}

Li, Heng ^{[1
]}

Chen, Zhongzhong ^{[2
]}

Coghlan, Avril ^{[1
]}

Coin, Lachlan James M. ^{[3
]}

Guo, Yiran ^{[2
]}

Heriche, Jean-Karim ^{[1
]}

Hu, Yafeng ^{[2
]}

Kristiansen, Karsten

Li, Ruiqiang ^{[2
,4
]}

Liu, Tao ^{[2
]}

Moses, Alan ^{[1
]}

Qin, Junjie ^{[2
]}

Vang, Soren ^{[5
,6
]}

Vilella, Albert J. ^{[7
]}

Ureta-Vidal, Abel ^{[7
]}

Bolund, Lars ^{[2
,8
]}

Wang, Jun ^{[2
,4
,8
]}

Durbin, Richard

机构：

[1] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England

[2] Chinese Acad Sci, Beijing Inst Genom, Beijing 101300, Peoples R China

[3] Univ London Imperial Coll Sci Technol & Med, Dept Epidemiol, London W2 1PG, England

[4] Univ So Denmark, Dept Biochem & Mol Biol, DK-5230 Odense, Denmark

[5] Univ Aarhus, Fac Hlth Sci, DK-8200 Aarhus, Denmark

[6] Univ Aarhus, Aarhus Univ Hosp, Res Unit Mol Med, DK-8200 Aarhus, Denmark

[7] EMBL, European Bioinformat Inst, Cambridge, England

[8] Univ Aarhus, Inst Human Genet, DK-8000 Aarhus C, Denmark

来源：

NUCLEIC ACIDS RESEARCH | 2008年 / 36卷

基金：

英国惠康基金;

关键词：

D O I：

10.1093/nar/gkm1005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

TreeFam (http://www.treefam.org) was developed to provide curated phylogenetic trees for all animal gene families, as well as orthologue and paralogue assignments. Release 4.0 of TreeFam contains curated trees for 1314 families and automatically generated trees for another 14 351 families. We have expanded TreeFam to include 25 fully sequenced animal genomes, as well as four genomes from plant and fungal outgroup species. We have also introduced more accurate approaches for automatically grouping genes into families, for building phylogenetic trees, and for inferring orthologues and paralogues. The user interface for viewing phylogenetic trees and family information has been improved. Furthermore, a new perl API lets users easily extract data from the TreeFam mysql database.

引用

页码：D735 / D740

页数：6

共 27 条

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