TcruziDB:: an integrated Trypanosoma cruzi genome resource

被引：12

作者：

Luchtan, M

Warade, C

Weatherly, DB

Degrave, WM

Tarleton, RL

Kissinger, JC ^{[1
]}

机构：

[1] Univ Georgia, Ctr Trop Emerging Global Dis, Athens, GA 30602 USA

[2] Univ Georgia, Dept Comp Sci, Athens, GA 30602 USA

[3] Inst Oswaldo Cruz, Dept Biochem & Mol Biol, BR-21045900 Rio De Janeiro, Brazil

[4] Univ Georgia, Dept Cellular Biol, Athens, GA 30602 USA

[5] Univ Georgia, Dept Genet, Athens, GA 30602 USA

来源：

NUCLEIC ACIDS RESEARCH | 2004年 / 32卷

关键词：

D O I：

10.1093/nar/gkh049

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

TcruziDB (http:/TcruziDB.org) is an integrated genome database for the parasitic organism Trypanosoma cruzi, the causative agent of Chagas' disease. The database currently incorporates all available sequence data (Genomic, BAC, EST) in a single user-friendly location. The database contains a variety of tools specifically designed for searching unannotated draft sequence via BLAST, keyword searches of pre-computed BLAST results, and protein motif searches. Release 1.0 of the database contains nearly 730 million bp of genome sequence from 1.1 million sequence reads generated by the TIGR-Karolinska-SBRI Trypanosoma cruzi Genome Consortium and 15 million bp of clustered EST and genomic sequence obtained from other sources. As annotation, microarray and proteomic data become available, the database will incorporate and integrate these data using the GUS (http://www.gusdb. org) relational framework.

引用

页码：D344 / D346

页数：3

共 10 条

[1] A random sequencing approach for the analysis of the Trypanosoma cruzi genome:: General structure, large gene and repetitive DNA families, and gene discovery [J].