Long-QT syndrome

被引：284

作者：

Roden, Dan M. ^{[1
,2
]}

机构：

[1] Vanderbilt Univ, Sch Med, Oates Inst Expt Therapeut, Dept Med, Nashville, TN 37232 USA

[2] Vanderbilt Univ, Sch Med, Oates Inst Expt Therapeut, Dept Pharmacol, Nashville, TN 37232 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2008年 / 358卷 / 02期

关键词：

D O I：

10.1056/NEJMcp0706513

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

After the sudden death of a 13-year-old girl while she was playing basketball, her family comes to the clinic for medical evaluation (Fig. 1). Her parents' resting electrocardiograms (ECGs) are normal, but her 9-year-old sister's ECG shows an abnormally long QT interval. There is a history of recurrent syncope in female relatives of the maternal grandmother, but there is no family history of other sudden deaths, the sudden infant death syndrome, drowning, or death from a motor vehicle accident. How should these family members be further evaluated and treated? Copyright © 2008 Massachusetts Medical Society.

引用

页码：169 / 176

页数：8

共 52 条

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Zipes, Douglas P. ;

Camm, A. John ;

Borggrefe, Martin ;

Buxton, Alfred E. ;

Chaitman, Bernard ;

Fromer, Martin ;

Gregoratos, Gabriel ;

Klein, George ;

Moss, Arthur J. ;

Myerburg, Robert J. ;

Priori, Silvia G. ;

Quinones, Miguel A. ;

Roden, Dan M. ;

Silka, Michael J. ;

Tracy, Cynthia ;

Smith, Sidney C., Jr. ;

Jacobs, Alice K. ;

Adams, Cynthia D. ;

Antman, Elliott M. ;

Anderson, Jeffrey L. ;

Hunt, Sharon A. ;

Halperin, Jonathan L. ;

Nishimura, Rick ;

Ornato, Joseph P. ;

Page, Richard L. ;

Riegel, Barbara ;

Priori, Silvia G. ;

Blanc, Jean-Jacques ;

Budaj, Andrzej ;

Camm, A. John ;

Dean, Veronica ;

Deckers, Jaap W. ;

Despres, Catherine ;

Dickstein, Kenneth ;

Lekakis, John ;

McGregor, Keith ;

Metra, Marco ;

Morais, Joao ;

Osterspey, Ady ;

Tamargo, Juan Luis ;

Zamorano, Jose Luis .

CIRCULATION, 2006, 114 (10) :E385-E484

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