Complete Nucleotide Sequence of Plasmid pTN48, Encoding the CTX-M-14 Extended-Spectrum β-Lactamase from an Escherichia coli O102-ST405 Strain

被引:16
作者
Billard-Pomares, Typhaine [1 ,2 ,8 ]
Tenaillon, Olivier [1 ,2 ]
Le Nagard, Herve [3 ,4 ]
Rouy, Zoe [5 ]
Cruveiller, Stephane [5 ]
Medigue, Claudine [5 ]
Arlet, Guillaume [6 ,7 ]
Denamur, Erick [1 ,2 ]
Branger, Catherine [1 ,2 ,8 ]
机构
[1] Univ Paris 07, INSERM, UMR S 722, F-75018 Paris, France
[2] Univ Paris Diderot, Fac Med, UMR S 722, F-75018 Paris, France
[3] Univ Paris 07, INSERM, UMR S 738, F-75018 Paris, France
[4] Univ Paris Diderot, UMR S 738, F-75018 Paris, France
[5] CEA Genoscope, Inst Genom, CNRS, Lab Genom Comparat,UMR 8030, Evry, France
[6] Univ Paris 06, Fac Med, Bacteriol Lab, ER8, Paris, France
[7] Hop Tenon, AP HP, Serv Microbiol Hyg, F-75970 Paris, France
[8] Hop Louis Mourier, AP HP, Serv Microbiol Hyg, F-92701 Colombes, France
关键词
MOLECULAR CHARACTERIZATION; PHYLOGENETIC SUBGROUP; VIRULENCE PLASMIDS; CLONE; RESISTANCE; EVOLUTION; GENE;
D O I
10.1128/AAC.01108-10
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The sequence of pTN48, a plasmid of the FII-FIB replicon type that encodes a CTX-M-14 enzyme in an Escherichia coli strain of the phylogenetic group D-2 O102-ST405 clone, was determined. pTN48 is, for the most part, a mosaic of virulence, antibiotic resistance, and addiction system modules found in various other plasmids. The presence of multiple addiction systems indicates that the plasmid should be stably maintained in the E. coli clone, favoring dissemination of the CTX-M-14 enzyme.
引用
收藏
页码:1270 / 1273
页数:4
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