Fusion needs more than SNAREs

被引：25

作者：

Almers, W ^{[1
]}

机构：

[1] Vollum Inst, Portland, OR 97201 USA

来源：

NATURE | 2001年 / 409卷 / 6820期

关键词：

D O I：

10.1038/35054637

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Force biological membranes close enough together and they will fuse. SNARE proteins are well suited to force proximity. But biochemical studies of yeast show that proximity is not the only requirement.

引用

页码：567 / 568

页数：2

共 11 条

[1] TRANSMITTER RELEASE FROM SYNAPSES - DOES A PREASSEMBLED FUSION PORE INITIATE EXOCYTOSIS [J].

ALMERS, W ;

TSE, FW .

NEURON, 1990, 4 (06) :813-818

[2] Structural insights into the molecular mechanism of Ca2+-dependent exocytosis [J].

Brunger, AT .

CURRENT OPINION IN NEUROBIOLOGY, 2000, 10 (03) :293-302

[3] The pathway of membrane fusion catalyzed by influenza hemagglutinin: Restriction of lipids, hemifusion, and lipidic fusion pore formation [J].

Chernomordik, LV ;

Frolov, VA ;

Leikina, E ;

Bronk, P ;

Zimmerberg, J .

JOURNAL OF CELL BIOLOGY, 1998, 140 (06) :1369-1382

[4] Postfusional regulation of cleft glutamate concentration during LTP at 'silent synapses' [J].

Choi, S ;

Klingauf, J ;

Tsien, RW .

NATURE NEUROSCIENCE, 2000, 3 (04) :330-336

[5] CALCIUM-INDUCED DESENSITIZATION OF ACETYLCHOLINE-RELEASE FROM SYNAPTOSOMES OR PROTEOLIPOSOMES EQUIPPED WITH MEDIATOPHORE, A PRESYNAPTIC MEMBRANE-PROTEIN [J].

ISRAEL, M ;

MEUNIER, FM ;

MOREL, N ;

LESBATS, B .

JOURNAL OF NEUROCHEMISTRY, 1987, 49 (03) :975-982

[6] Membrane fusion and exocytosis [J].

Jahn, R ;

Südhof, TC .

ANNUAL REVIEW OF BIOCHEMISTRY, 1999, 68 :863-911

[7] Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs [J].

Nickel, W ;

Weber, T ;

McNew, JA ;

Parlati, F ;

Söllner, TH ;

Rothman, JE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (22) :12571-12576

[8] Trans-complex formation by proteolipid channels in the terminal phase of membrane fusion [J].

Peters, C ;

Bayer, MJ ;

Bühler, S ;

Andersen, JS ;

Mann, M ;

Mayer, A .

NATURE, 2001, 409 (6820) :581-588

[9] Ca2+/calmodulin signals the completion docking and triggers a late step of vacuole fusion [J].

Peters, C ;

Mayer, A .

NATURE, 1998, 396 (6711) :575-580

[10] Defining the functions of trans-SNARE pairs [J].

Ungermann, C ;

Sato, K ;

Wickner, W .

NATURE, 1998, 396 (6711) :543-548

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