Multiple C-H activations to construct biologically active molecules in a process completely free of organohalogen and organometallic components

被引：436

作者：

Li, Bi-He ^{[1
]}

Tian, Shi-Liang ^{[1
]}

Fang, Zhao ^{[1
]}

Shi, Zhang-Jie ^{[1
]}

机构：

[1] Peking Univ, Coll Chem, Beijing 100871, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 06期

关键词：

C-C coupling; C-H activation; dehydrogenation; homogeneous catalysis; palladium;

D O I：

10.1002/anie.200704092

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Step by step: Highly selective cross dehydrogenase arylation of acetanilides was developed to construct biaryls under mild condition. With this method, different aryl C-H bonds were activated in sequential reactions to construct functionalized carbazoles (see scheme), which are present as key structural units in various biological molecules and organic optical materials. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1115 / 1118

页数：4

共 66 条

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