Acute hemodynamic effects and home therapy using a novel pulsed nasal nitric oxide delivery system in children and young adults with pulmonary hypertension

被引：29

作者：

Ivy, DD

Parker, D

Doran, A

Parker, D

Kinsella, JP

Abman, SH

机构：

[1] Childrens Hosp, Denver, CO 80218 USA

[2] Univ Colorado, Sch Med, Sect Cardiol, Pediat Heart Lung Ctr, Boulder, CO 80309 USA

[3] Univ Colorado, Sch Med, Sect Pulm, Pediat Heart Lung Ctr, Boulder, CO 80309 USA

[4] Univ Colorado, Sch Med, Sect Neonatol, Pediat Heart Lung Ctr, Boulder, CO 80309 USA

[5] Univ Colorado, Sch Med, Dept Pediat, Pediat Heart Lung Ctr, Boulder, CO 80309 USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2003年 / 92卷 / 07期

关键词：

D O I：

10.1016/S0002-9149(03)00910-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In 26 patients, we evaluated a novel pulsed nasal delivery system for nitric oxide (NO) that, in the short term, was as effective as continuous delivery for decreasing pulmonary artery pressure and pulmonary vascular resistance. In 2 patients, NO delivered in the home using this pulsing system was well tolerated for up to 2 years. The long-term safety, efficacy, and acceptability of NO delivered in the home remains to be studied. (C) 2003 by Excerpta Medica, Inc.

引用

页码：886 / 890

页数：5