Protein Microarray for profiling antibody responses to Yersinia pestis live vaccine

被引：78

作者：

Li, B

Jiang, LX

Song, QF

Yang, JX

Chen, ZL

Guo, ZB

Zhou, DS

Du, ZM

Song, YJ

Wang, J

Wang, HX

Yu, SY

Wang, J

Yang, RF ^{[1
]}

机构：

[1] Acad Mil Med Sci, Inst Microbiol & Epidemiol, Army Ctr Microbial Detect & Res, Natl Ctr Biomed Anal,Lab Analyt Microbiol, Beijing 100071, Peoples R China

[2] Chinese Acad Sci, Beijing Genom Inst, Beijing 100101, Peoples R China

[3] Med Univ S, Guangzhou, Peoples R China

[4] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

来源：

INFECTION AND IMMUNITY | 2005年 / 73卷 / 06期

关键词：

D O I：

10.1128/IAI.73.6.3734-3739.2005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A protein microarray representing 149 Yersinia pestis proteins was developed to profile antibody responses in EV76-immunized rabbits. Antibodies to 50 proteins were detected. There are 11 proteins besides F1 and V antigens to which the predominant antibody response occurred, and these proteins show promise for further evaluation as candidates for subunit vaccines and/or diagnostic antigens.

引用

页码：3734 / 3739

页数：6

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