Optimization of optode arrangements for diffuse optical tomography: A singular-value analysis

被引:151
作者
Culver, JP
Ntziachristos, V
Holboke, MJ
Yodh, AG
机构
[1] Univ Penn, Dept Phys, Philadelphia, PA 19104 USA
[2] Univ Penn, Dept Astron, Philadelphia, PA 19104 USA
关键词
D O I
10.1364/OL.26.000701
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We develope a method to optimize the resolution of diffuse optical tomographic instruments. Singular-value analysis of the tomographic weight matrix associated with specific data types, geometries, and optode arrangements is shown to provide a measure of image resolution. We achieve optimization of device configuration by monitoring the resolution measure described. We introduce this idea and demonstrate its utility by optimizing the spatial sampling interval and field-of-view parameters in the parallel-plane transmission geometry employed for diffuse optical breast imaging. We also compare resolution in transmission and remission geometries. (C) 2001 Optical Society of America.
引用
收藏
页码:701 / 703
页数:3
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