Combinatorial material mechanics: High-throughput polymer synthesis and nanomechanical screening

被引:80
作者
Tweedie, CA
Anderson, DG
Langer, R
Van Vliet, KJ
机构
[1] MIT, Dept Mat Sci & Engn, Cambridge, MA 02139 USA
[2] MIT, Dept Chem Engn, Cambridge, MA 02139 USA
关键词
D O I
10.1002/adma.200501142
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Combinatorial materials science requires parallel advances in materials characterization. A high-throughput nanoscale synthesis/nanomechanical profiling approach capable of accurately screening the mechanical properties of 1,700 photopolymerizable materials (see Figure, scale bar: 100 mu m) within a large, discrete polymer library is presented. This approach enables rapid correlation of polymer composition, processing, and structure with mechanical performance metrics.
引用
收藏
页码:2599 / +
页数:7
相关论文
共 29 条
[1]   Combinatorial materials science: What's new since Edison? [J].
Amis, EJ ;
Xiang, XD ;
Zhao, JC .
MRS BULLETIN, 2002, 27 (04) :295-297
[2]   Biomaterial microarrays: rapid, microscale screening of polymer-cell interaction [J].
Anderson, DG ;
Putnam, D ;
Lavik, EB ;
Mahmood, TA ;
Langer, R .
BIOMATERIALS, 2005, 26 (23) :4892-4897
[3]   Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells [J].
Anderson, DG ;
Levenberg, S ;
Langer, R .
NATURE BIOTECHNOLOGY, 2004, 22 (07) :863-866
[4]  
Ashby M.F., 2011, Materials selection in mechanical design, V4th
[5]   Nanoindentation and adhesion of sol-gel-derived hard coatings on polyester [J].
Chan, CM ;
Cao, GZ ;
Fong, H ;
Sarikaya, M ;
Robinson, T ;
Nelson, L .
JOURNAL OF MATERIALS RESEARCH, 2000, 15 (01) :148-154
[6]   Size effects on the onset of plastic deformation during nanoindentation of thin films and patterned lines [J].
Choi, Y ;
Van Vliet, KJ ;
Li, J ;
Suresh, S .
JOURNAL OF APPLIED PHYSICS, 2003, 94 (09) :6050-6058
[7]   Computational modeling of the forward and reverse problems in instrumented sharp indentation [J].
Dao, M ;
Chollacoop, N ;
Van Vliet, KJ ;
Venkatesh, TA ;
Suresh, S .
ACTA MATERIALIA, 2001, 49 (19) :3899-3918
[8]   A method for interpreting the data from depth-sensing indentation instruments [J].
Doerner, M. F. ;
Nix, W. D. .
JOURNAL OF MATERIALS RESEARCH, 1986, 1 (04) :601-609
[9]   Surface probe measurements of the elasticity of sectioned tissue, thin gels and polyelectrolyte multilayer films: Correlations between substrate stiffness and cell adhesion [J].
Engler, AJ ;
Richert, L ;
Wong, JY ;
Picart, C ;
Discher, DE .
SURFACE SCIENCE, 2004, 570 (1-2) :142-154
[10]   Determination of elastoplastic properties by instrumented sharp indentation [J].
Giannakopoulos, AE ;
Suresh, S .
SCRIPTA MATERIALIA, 1999, 40 (10) :1191-1198