N-Trihalomethyl derivatives of benzimidazole, benzotriazole and indazole

被引：31

作者：

Yagupolskii, LM ^{[1
]}

Fedyuk, DV ^{[1
]}

Petko, KI ^{[1
]}

Troitskaya, VI ^{[1
]}

Rudyk, VI ^{[1
]}

Rudyuk, VV ^{[1
]}

机构：

[1] Natl Acad Sci Ukraine, Inst Organ Chem, UA-02094 Kiev, Ukraine

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2000年 / 106卷 / 02期

关键词：

heterocycles; dithiocarboxylates; trihalomethylation; azoles; triazoles;

D O I：

10.1016/S0022-1139(00)00321-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

1-Chlorodifluoromethyl- and 1-trifluoromethyl-substituted 2-methylbenzimidazoles and benzotriazoles were obtained by chlorination of the corresponding methyl 1-azoledithiocarboxylates and subsequent fluorination of the resulting 1-trichloromethyl derivatives. The condensation of N-sodium salts of 2-alkylbmzimidazoles and indazole with CF2Br2 was shown to afford the corresponding 1-bromodifluoromethylated compounds. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：181 / 187

页数：7

共 9 条

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