Immunoglobulin-polydiacetylene sol-gel nanocomposites as solid-state chromatic biosensors

被引：79

作者：

Gill, I

Ballesteros, A

机构：

[1] BiosynTech, Nutley, NJ 07110 USA

[2] CSIC, Inst Catalysis, Dept Biocatalysis, E-28049 Madrid, Spain

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 28期

关键词：

biosensors; liposomes; nanocomposites; polydiacetylenes; sol-gel processes;

D O I：

10.1002/anie.200351290

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Rugged and sensitive chromatic solid-state materials are obtained by encapsulation of bichromic polydiacetylene-phospholipid liposomes appended with immunoglobulins in hybrid silica-siloxane sol-gel polymers. The resulting composites undergo dramatic and visible blue-to-red color transitions upon exposure to the corresponding antigens (see picture) and have applications as sensors.

引用

页码：3264 / 3267

页数：4

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