A cost of disease resistance: paradigm or peculiarity?

被引：89

作者：

Brown, JKM ^{[1
]}

机构：

[1] John Innes Ctr Plant Sci Res, Dept Dis & Stress Biol, Norwich NR4 7UH, Norfolk, England

来源：

TRENDS IN GENETICS | 2003年 / 19卷 / 12期

关键词：

D O I：

10.1016/j.tig.2003.10.008

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Disease is one of the main driving forces of biological evolution. Parasites cause natural selection for disease resistance in populations of their hosts. Why then are all organisms susceptible to some parasites? One explanation is that resistance to disease is costly, reducing the fitness of the host in the absence of disease. A recent article shows that such costs might have helped to maintain polymorphism at a resistance locus. Other work, however, has questioned whether the costs of resistance are indeed necessary to account for polymorphism in host-parasite interactions.

引用

页码：667 / 671

页数：5

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