Human cytomegalovirus resistance to antiviral drugs

被引:168
作者
Gilbert, C
Boivin, G
机构
[1] CHUL, CHUQ, Res Ctr Infect Dis, Ste Foy, PQ G1V 4G2, Canada
[2] Univ Laval, Dept Med Biol, Ste Foy, PQ G1K 7P4, Canada
关键词
D O I
10.1128/AAC.49.3.873-883.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
引用
收藏
页码:873 / 883
页数:11
相关论文
共 142 条
[1]  
[Anonymous], 1996, Arch Ophthalmol, V114, P23
[2]   Human cytomegalovirus double resistance in a donor-positive/recipient-negative lung transplant patient with an impaired CD4-mediated specific immune response [J].
Baldanti, F ;
Lilleri, D ;
Campanini, G ;
Comolli, G ;
Ridolfo, AL ;
Rusconi, S ;
Gerna, G .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2004, 53 (03) :536-539
[3]   Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recovered from patients with AIDS [J].
Baldanti, F ;
Underwood, MR ;
Stanat, SC ;
Biron, KK ;
Chou, SW ;
Sarasini, A ;
Silini, E ;
Gerna, G .
JOURNAL OF VIROLOGY, 1996, 70 (03) :1390-1395
[4]  
Baldanti F, 1998, ANTIMICROB AGENTS CH, V42, P444
[5]   Emergence of multiple drug-resistant human cytomegalovirus variants in 2 patients with human immunodeficiency virus infection unresponsive to highly active antiretroviral therapy [J].
Baldanti, F ;
Paolucci, S ;
Parisi, A ;
Meroni, L ;
Gerna, G .
CLINICAL INFECTIOUS DISEASES, 2002, 34 (08) :1146-1149
[6]   Mutations in the UL97 ORF of ganciclovir-resistant clinical cytomegalovirus isolates differentially affect GCV phosphorylation as determined in a recombinant vaccinia virus system [J].
Baldanti, F ;
Michel, D ;
Simoncini, L ;
Heuschmid, M ;
Zimmermann, A ;
Minisini, R ;
Schaarschmidt, P ;
Schmid, T ;
Gerna, G ;
Mertens, T .
ANTIVIRAL RESEARCH, 2002, 54 (01) :59-67
[7]   A 3-NUCLEOTIDE DELETION IN THE UL97 OPEN READING FRAME IS RESPONSIBLE FOR THE GANCICLOVIR RESISTANCE OF A HUMAN CYTOMEGALOVIRUS CLINICAL ISOLATE [J].
BALDANTI, F ;
SILINI, E ;
SARASINI, A ;
TALARICO, CL ;
STANAT, SC ;
BIRON, KK ;
FURIONE, M ;
BONO, F ;
PALU, G ;
GERNA, G .
JOURNAL OF VIROLOGY, 1995, 69 (02) :796-800
[8]   Antiviral drugs [J].
Balfour, HH .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (16) :1255-1268
[9]   Viral escape and T-cell immunity during ganciclovir treatment of cytomegalovirus infection: Case report of a pancreatico-renal transplant recipient [J].
Benz, C ;
Holz, G ;
Michel, D ;
Awerkiew, S ;
Dries, V ;
Stippel, D ;
Goeser, T ;
Busch, DH .
TRANSPLANTATION, 2003, 75 (05) :724-727
[10]   A CONSERVED 3'-]5' EXONUCLEASE ACTIVE-SITE IN PROKARYOTIC AND EUKARYOTIC DNA-POLYMERASES [J].
BERNAD, A ;
BLANCO, L ;
LAZARO, JM ;
MARTIN, G ;
SALAS, M .
CELL, 1989, 59 (01) :219-228