Why opioids and sedatives may prolong life rather than hasten death after ventilator withdrawal in critically ill patients

被引：20

作者：

Bakker, Jan ^{[1
]}

Jansen, Tim C. ^{[1
]}

Lima, Alex ^{[1
]}

Kompanje, Erxvin J. O. ^{[1
]}

机构：

[1] Erasmus MC Univ Med Ctr, Dept Intens Care, NL-3000 CA Rotterdam, Netherlands

来源：

AMERICAN JOURNAL OF HOSPICE & PALLIATIVE MEDICINE | 2008年 / 25卷 / 02期

关键词：

palliative care; tissue hypoxia; opioids;

D O I：

10.1177/1049909108315511

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

The process of death in patients in whom cardiorespiratory Support is withdrawn is related to the occurrence of tissue hypoxia that results from an imbalance between the demand for oxygen and the delivery of oxygen to the organs. Limiting the demand for oxygen may thus delay the occurrence Of tissue hypoxia. Because the. demand for oxygen increases significantly after ventilator withdrawal and because sedatives and opioids are known to decrease the demand for oxygen in patients with cardiorespiratory distress, these agents might thus actually prolong life rather than hasten death.

引用

页码：152 / 154

页数：3